Based on the linked source; automatically prepared and checked against the original report.
Study rationale
This preprint protocol addresses a gap in rural South African evidence by comparing cardiovascular risk profiles according to mobility status. It focuses on wheelchair users and ambulatory adults in Thulamela Municipality, Limpopo Province. The investigators will examine blood pressure, waist circumference, physical activity, and sedentary behavior, while testing whether mobility status is independently associated with hypertension. The record emphasizes that this is a cross-sectional study protocol, not peer-reviewed evidence.
Planned measurements
The planned sample comprises 210 adults: 70 wheelchair users and 140 ambulatory controls. Recruitment will use purposive and convenience sampling through rural networks. Researchers will take seated blood pressure and seated waist circumference measurements to standardize assessment across groups. Physical activity and sedentary time will be measured with the LTPAQ-SCI and IPAQ-SF. Outcomes will be harmonized into weekly minutes of moderate-to-vigorous physical activity.
Analysis plan
Planned comparisons will use t-tests or Mann-Whitney U tests, followed by logistic regression controlling for clinical and demographic confounders.
