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Study validates a submaximal test for estimating oxygen uptake in wheelchair users with spinal cord injury

A Swedish cross-sectional study assessed whether the Holmlund-Grooten submaximal test could estimate peak oxygen uptake in wheelchair users with motor-complete spinal cord injury.

Study validates a submaximal test for estimating oxygen uptake in wheelchair users with spinal cord injury

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Study purpose and setting

Researchers evaluated the Holmlund-Grooten submaximal test in wheelchair users with motor-complete spinal cord injury. The study examined criterion validity, measurement error and minimal detectable change. It took place at an outpatient rehabilitation centre in Stockholm, Sweden, and used indirect calorimetry to measure peak and submaximal oxygen uptake.

Participants and prediction model

The analysis included 63 people with motor-complete spinal cord injury, including 16 females. Researchers used backward linear regression incorporating heart rate, power output and demographic variables to predict absolute peak oxygen uptake. The final model retained sex, injury level, heart rate and power output, explaining 77% of variance after adjustment.

Validity and reported implementation

The test showed excellent criterion validity, with an intraclass correlation coefficient of 0.88 and a 95% confidence interval from 0.83 to 0.94. The reported standard error of measurement was 0.05 L·min⁻¹, and the minimal detectable change was 0.13 L·min⁻¹. No adverse events were reported. The authors concluded that the test could be implemented clinically and provided an Excel calculator for males and females with tetra- or paraplegia.

Sources & further reading

Europe PMC — original report

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